Litaba
- Sefuba sa mast cell ke eng likatseng
- Mefuta ea lihlahala tsa feline mast cell
- Sefuba sa mast cell se khaohileng
- hlahala ea visceral mast
- Matšoao a lihlahala tsa mast cell ka likatse
- Matšoao a lihlahala tsa mast cell tse ikhethileng likatseng
- Matšoao a li-tumor tsa visceral mast likatseng
- Tlhahlobo ea hlahala ea feline mast cell tumor
- Tlhahlobo ea hlahala ea likotoana tse sehiloeng ka har'a likatse
- Ho lemoha lihlahala tsa visceral mast ka likatse
- Kalafo ea lihlahala tsa mast cell ka likatse
- Kalafo ea lihlahala tsa methapo e se nang likatse likatse
- Kalafo ea li-tumor tsa visceral mast likatseng
Lihlahala tsa lisele tse ngata likatseng li ka hlahisa mefuta e 'meli e fapaneng: ea ho itšeha le ea visceral. Sefuba sa mast cell se khaohang ke se atisang ho feta ebile ke mofuta oa bobeli oa kankere e kotsi e atileng haholo ho likatse. Lihlahala tsa li-visceral mast li hlaha haholo ka spleen, leha e ka hlaha le libakeng tse ling joalo ka mala.
Tlhahlobo e entsoe ke cytology kapa biopsy maemong a lihlahala tsa methapo e metle, le ka cytology, tlhahlobo ea mali le tlhahlobo ea litšoantšo litlhahisong tsa visceral mast cell. Kalafo e etsoa ka ho buuoa maemong ana ka bobeli, leha ho sa bontšoe mefuta e meng ea li-visceral mast cell tumor, ho sebelisa chemotherapy le lithethefatsi tse ts'ehetsang ho ntlafatsa boleng ba bophelo ba likatse tse nang le lihlahala tsa mast. Tsoela pele ho bala sengoloa sa PeritoAnimal ho ithuta haholoanyane ka hlahala ea mast cell, matšoao a eona, kalafo le ponelopele.
Sefuba sa mast cell ke eng likatseng
Mastocytoma ke e 'ngoe ea mefuta ea lihlahala tse ka amang likatse tse nang le pheteletso ya sele e ngata e feteletsang. Lisele tsa 'mele ke lisele tse tsoang' meleng oa masapo ho tsoa ho li-premators tsa hematopoietic mme li ka fumanoa letlalong, lisele tse sebetsang, masapo a meno le phefumoloho.
Na lisele tse sireletsang Mohala oa pele khahlano le mahlahana a tšoaetsanoang le li-granules tsa ona li na le lintho tse lumellanang le khatello ea mmele le ho ruruha, joalo ka histamine, TNF-α, IL-6, proteases, jj.
Ha hlahala ea lisele tsena e hlaha, lintho tse ka har'a granules tsa tsona li lokolloa ka tsela e feteletsang, li baka litlamorao tsa lehae kapa tsa sistimi e ka lebisang lipontšong tse fapaneng tsa bongaka ho latela sebaka sa tsona.
Mefuta ea lihlahala tsa feline mast cell
Likatseng, lihlahala tsa li-mast cell li ka fokotsoa ha li le letlalong; kapa visceral, ha e le ka har'a viscera ea kahare.
Sefuba sa mast cell se khaohileng
Ke hlahala ea bobeli e kotsi hangata haholo likatse le ea bone har'a lihlahala tsohle tsa feline. Likatse tsa Siamese li bonahala li na le monyetla oa ho hlokofatsoa ke lihlahala tsa methapo e metle. Li teng litsela tse peli ea lihlahala tsa 'mele tse arohaneng ho latela litšobotsi tsa tsona tsa nalane ea nalane:
- mastocytosis: E hlaha haholo-holo likatseng tse fetang lilemo tse 9 mme e ikarola ka sebopeho se kopaneng (e atisang ho ba teng ebile e le kotsi, ho fihlela ho 90% ea linyeoe) le sebopeho se fapaneng (se kotsi haholo, se kenella le ho baka metastasis).
- Histori: E etsahala pakeng tsa lilemo tse 2 le 10.
hlahala ea visceral mast
Lihlahala tsena tsa mast li ka fumanoa ho litho tsa parenchymal joaloka:
- Spleen (khafetsa).
- Mala a manyane.
- Lymph nodes tse bohareng.
- Lymph node tsa Mesenteric.
Haholo-holo e ama likatse tsa khale hara O lilemo li 9 le 13 bomolimo.
Matšoao a lihlahala tsa mast cell ka likatse
ho latela mofuta oa feline mast cell hlahala, matšoao a ka fapana, joalo ka ha re tla bona ka tlase.
Matšoao a lihlahala tsa mast cell tse ikhethileng likatseng
Ho ka ba joalo ka li-tumor tsa methapo e se nang likatse matšoele a masoha kapa a mangata (20% ea linyeoe). Li ka fumanoa hloohong, molaleng, sefubeng kapa maotong, hara tse ling.
Ho na le maqhutsu tseo hangata e leng:
- Ho hlalosoa.
- 0.5-3 cm bophara.
- Ha e na mmala kapa pinki.
Ba bang matšoao a bongaka tse ka hlahang sebakeng sa hlahala ke:
- Erythema.
- Lisosa tsa ka ntle.
- Ho hlohlona ho sa khaotseng.
- Ho intša kotsi.
- Ho ruruha.
- Edema e ka tlasa letlalo.
- Karabelo ea anaphylactic.
Li-nodule tsa nalane ea nalane ea nalane ea nalane ea nalane ea nalane hangata lia nyamela ka boithatelo.
Matšoao a li-tumor tsa visceral mast likatseng
Likatse tse nang le lihlahala tsa visceral mast li bontša matšoao a lefu la tsamaiso, joalo ka:
- Ho hlatsa.
- Ho tepella maikutlo.
- Ho ipolaisa tlala.
- Ho fokotsa boima ba 'mele.
- Letšollo.
- Hyporexia.
- Ho phefumoloha ho thata haeba ho na le mokokotlo oa mokokotlo.
- Splenomegaly (boholo ba spleen e atolositsoeng).
- Li-Ascite.
- Hepatomegaly (sebete se atolositsoeng).
- Phokolo ea mali (14-70%).
- Mastocytosis (31-100%).
Ha katse e hlahisa liphetoho tsa spleen, joalo ka ho holisa, maqhutsu, kapa karolo e akaretsang ea setho, ntho ea pele eo u ka nahanang ka eona ke hlahala ea sele e kholo.
Tlhahlobo ea hlahala ea feline mast cell tumor
Ho hlahlojoa ho tla itšetleha ka mofuta oa mast cell tumor eo ngaka ea liphoofolo e belaelang hore feline e ka ba le eona.
Tlhahlobo ea hlahala ea likotoana tse sehiloeng ka har'a likatse
Ho belaelloa lihlahala tsa 'mele tse arohaneng likatse ha ho hlaha nodule e nang le litšobotsi tse hlalositsoeng kaholimo, e netefatsoa ke cytology kapa biopsy.
Histicitic mast cell tumor ke eona e thata ka ho fetisisa ho e fumana ka cytology ka lebaka la likarolo tsa eona tsa lisele, granularity e sa hlakileng le boteng ba lisele tsa lymphoid.
Re lokela ho elelloa hore, ho feline eosinophilic granuloma, lisele tse kholo li kanna tsa hlaha hape, tse ka lebisang ho phumano e fosahetseng.
Ho lemoha lihlahala tsa visceral mast ka likatse
O ho khetholla phapang ea li-tumor tsa li-feline visceral mast, haholo-holo tsa spleen, li kenyelletsa lits'ebetso tse latelang:
- Splenite.
- Spleen ea lisebelisoa.
- Hemangiosarcoma.
- Nodular hyperplasia.
- Lymphoma.
- Lefu la Myeloproliferative.
Palo ea mali, biochemistry le liteko tsa ho nka litšoantšo li bohlokoa ho fumana lihlahala tsa visceral mast cell:
- Teko ea mali: tekong ea mali, mastocytosis le khaello ea mali li ka belaelloa. Haholo-holo boteng ba mastocytosis, e leng tšobotsi ea ts'ebetso ena likatseng.
- Mpa ea ka mpeng: Ultrasound e ka lemoha splenomegaly kapa mala a 'mala' me ea batla metastases ho mesenteric lymph node kapa litho tse ling tse joalo ka sebete. E boetse eu lumella ho bona liphetoho ho spleen parenchyma kapa li-nodule.
- X-ray sefubeng: CXR e re lumella ho bona boemo ba matšoafo, ho batla metastases, ho qhekella ha 'mele kapa liphetoho ho cranial mediastinum.
- Cytology: Ts'oaetso e ntle ea nalane ea cytology ho spleen kapa mala e ka khetholla hlahala ea sele ea mast ho tsoa lits'ebetsong tse ling tse hlalositsoeng ho khethollo ea phapang. Haeba e etsoa ka mokokotlo kapa mokelikeli oa peritoneal, ho ka bonoa lisele tsa mast le li-eosinophil.
Kalafo ea lihlahala tsa mast cell ka likatse
Kalafo e lokelang ho lateloa e tla hlahisa mefuta e fapaneng ho latela mofuta oa hlahala ea mast cell e lokelang ho phekoloa.
Kalafo ea lihlahala tsa methapo e se nang likatse likatse
Kalafo ea sehlaha sa mast cell se entsoe ka ts'ebetso ea ho tlosa, esita le maemong a li-histiocytic, tse atisang ho khutlela morao ka boithaopo.
Ho buuoa hoa phekola 'me ho tlameha ho etsoa ka ho etsa resection ea lehae, maemong a lisele tse kholo, le ka maqhubu a mabifi maemong a fapaneng. Ka kakaretso, ho tlosoa hoa lehae e nang le mahlakore a pakeng tsa 0,5 le 1 cm e khothalletsoa bakeng sa hlahala efe kapa efe ea methapo e fumanoang ke cytology kapa biopsy.
Ho ipheta ha lihlahala tsa methapo ea mmele ho sa tloaelehang ho fumaneha haholo, leha ho tlosoa ho sa phethahalang.
Kalafo ea li-tumor tsa visceral mast likatseng
THE ho tlosoa hoa ho buoa ea visceral mast cell tumor e etsoa ka likatse tse nang le mala a 'mele kapa spleen ntle le metastases kae kapa kae. Pele o tlosoa, the tšebeliso ea li-antihistamine joalo ka cimetidine kapa chlorpheramine ho kgothaletswa ho fokotsa menyetla ea ho senyeha ha lisele tsa 'mele, tse ka bakang mathata joalo ka liso tsa ka mpeng, ho koala se sa tloaelehang le hypotension.
Nako e tloaelehileng ea ho pholoha kamora splenectomy e lipakeng Likhoeli tse 12 le 19, empa lintho tse mpe tse boletsoeng esale pele li kenyelletsa likatse tse nang le anorexia, ho theola boima ba 'mele haholo, phokolo ea mali, mastocythemia le metastasis.
Kamora ho buuoa, hangata e fuoa chemotherapy e tlatsanang le prednisolone, vinblastine kapa lomustine.
Maemong a metastasis kapa ho nka karolo hoa sistimi, prednisolone ea molomo e ka sebelisoa ka litekanyo tsa 4-8 mg / kg lihora tse ling le tse ling tsa 24-48. Haeba ho hlokahala moemeli oa chemotherapeutic, chlorambucil e ka sebelisoa ka molomo ka tekanyo ea 20 mg / m2 libeke tse ling le tse ling tse peli.
Ho ntlafatsa matšoao a likatse tse ling, lithethefatsi tsa antihistamine ho fokotsa asiti e feteletseng ea gastric, ho nyekeloa ke pelo le kotsi ea liso tsa ka maleng, antiemetics, litakatso tsa takatso ea lijo kapa li-analgesics.
Kaha joale u tseba ntho e ngoe le e ngoe ka lihlahala tsa feline mast cell, re fana ka maikutlo a video e latelang mabapi le mafu a atileng haholo likatseng:
Sengoloa sena se reretsoe ho fana ka tlhaiso-leseling feela, ho PeritoAnimal.com.br ha re khone ho fana ka kalafo ea bongaka ba liphoofolo kapa ho etsa mofuta ofe kapa ofe oa tlhahlobo. Re fana ka maikutlo a hore o ise phoofolo ea lapeng ho ngaka ea liphoofolo haeba e ka ba le boemo bofe kapa bofe bo sa thabiseng.
Haeba u batla ho bala lingoliloeng tse ling tse tšoanang le Matšoao a lisele tse ngata likatseng - Matšoao, kalafo le ponelopele, re khothaletsa hore o kenye karolo ea rona ea mathata a mang a bophelo bo botle.