Litaba
- Ke eng mme ke eng e bakang mafu a ho ruruha likatse?
- Na ho na le khethollo ea morabe kapa lilemo ho nts'etsopele ea feline IBD?
- Matšoao a lefu la ho ruruha ha mala likatseng
- Ho lemoha Mafu a Ho Ruruha ha Likokoana-hloko
- Phekolo ea mafu a ho ruruha a mala ka likatse
- kalafo ea lijo
- Kalafo ea bongaka
Ho ruruha mala kapa IBD ka likatse e na le pokello ea lisele tsa ho ruruha ka har'a mucosa ea mala. Pokello ena e ka ba li-lymphocyte, lisele tsa lero la mali kapa li-eosinophil. Likatseng, ka linako tse ling ho tsamaea le ho ruruha ha manyeme le / kapa sebete, ka hona e bitsoa feline triad. Matšoao a bongaka ke matšoao a akaretsang a bothata ba tšilo ea lijo, leha ho hlatsa le ho theola boima ba 'mele ho etsahala khafetsa, ho fapana le letšollo le sa foleng le atisang ho hlaha lintja.
Tlhatlhobo e ntle ea phapang e tlameha ho etsoa lipakeng tsa mafu a mang a hlahisang matšoao a ts'oanang, mme tlhahlobo e hlakileng e fumanoa ka histopathology. O kalafo e tla ba ka lijo tse itseng tse kopaneng le ts'ebeliso ea litlhare.
Tsoela pele ho bala sengoloa sena sa PeritoAnimal, moo re tla hlalosa seo u hlokang ho tseba ka sona Lefu la ho ruruha ha Likokoana-hloko - Matšoao le Phekolo.
Ke eng mme ke eng e bakang mafu a ho ruruha likatse?
Lefu la ho ruruha likatse kapa IBD ke Boloetse bo sa foleng ba ho ruruha bo sa tsejoeng. Nako le nako, e ka kenyelletsa mala a maholo kapa mpa mme ea amahanngoa le pancreatitis le / kapa cholangitis, e bitsoang feline triad.
Ho lefu la 'mele oa ho ruruha, ho na le ho kenella ha lisele tsa ho ruruha (li-lymphocyte, lisele tsa plasma kapa li-eosinophil) ka lamina propria ea lera la mucosal la mala, le ka fihlelang likarolo tse tebileng. Le ha tšimoloho e sa tsejoe, ho na le likhopolo-taba tse tharo mabapi le Lisosa tsa Mafu a Ho Ruruha ha Likatse:
- Phetoho ea boits'oaro khahlanong le epithelium ea mala ka boeona.
- Karabelo ho li-antigen tsa baktheria, parasite, kapa tsa phepo e tsoang maling lumen.
- Ho hloleha ho kenella hoa mucosa ea mala, e bakang ho pepeseha ho hoholo ho li-antigen tsena.
Na ho na le khethollo ea morabe kapa lilemo ho nts'etsopele ea feline IBD?
Ha ho na lilemo tse ikhethang. Le ha hangata e bonoa likatseng tse lilemong tse mahareng, likatse tse nyane le tse holileng le tsona li ka ameha. Ka lehlakoreng le leng, ho na le khethollo ea morabe likatse tsa Siamese, Persia le Himalaya.
Matšoao a lefu la ho ruruha ha mala likatseng
Ha ho ruruha ho hlaha ka maleng, matšoao a kliniki a ts'oana haholo le a mala a mala, hobane ha a atise ho likatse tse holileng, ha a khethehe feela. Kahoo, matšoao a kliniki a bontšang hore katse e nang le mafu a ho ruruha ke:
- Ho ipolaisa tlala kapa takatso e tloaelehileng ea lijo.
- Ho fokotsa boima ba 'mele.
- Ho hlatsa kapa ho hlatsa.
- Letšollo le lenyenyane.
- Letšollo le leholo haeba sena le sona sea ameha, hangata ka mali ka setulong.
Ha re opa ka mpeng, re ka 'na ra hlokomela keketseho ea ho tsitsa ha mala a mala kapa ho holisa li-lymph node tsa mesenteric.
Ho lemoha Mafu a Ho Ruruha ha Likokoana-hloko
Tlhatlhobo e hlakileng ea IBD ea feline e fumanoa ka ho kopanya nalane e ntle, tlhahlobo ea 'mele, tlhahlobo ea laboratori, tlhahlobo ea litšoantšo le histopathology ea li-biopsies. Hoa hlokahala ho etsa file ea teko ea mali le biochemistry, T4 detection, urinalysis, le radiography ea mpa ho thibela mafu a systemic a kang hyperthyroidism, lefu la liphio kapa ho hloleha ha sebete.
Ka linako tse ling ho ka bonoa CBC ea ho ruruha ho sa foleng ka keketseho ea li-neutrophil, monocyte le li-globulin. Haeba ho na le khaello ea vithamine B12, sena se ka supa hore bothata bo karolong ea ho qetela ea mala a manyane (ileum). Ka lehlakoreng le leng, radiography ea mpeng e ka lemoha litopo tsa kantle ho naha, likhase kapa ileus e shoeleng litho. Leha ho le joalo, mpa ea ultrasound ke tlhatlhobo ea bohlokoa ka ho fetisisa ea ho nka litšoantšo, ho khona ho bona botenya ba lebota la mala, haholoholo mucosa, esita le ho e metha.
Ha ho atisehe ho kula ha mala ka likatse hore boqapi ba mala bo lahlehile, joalo ka ha ho ka etsahala ka hlahala ea mala (lymphoma). Hape hoa khonahala ho hlokomela keketseho ea mesenteric lymph node 'me, ho latela boholo le sebopeho sa tsona, hore na li ruruhile kapa li na le hlahala.
Tlhahlobo e hlakileng le e fapaneng ea lymphoma e tla fumanoa ka tlhahlobo ea hae ea histopathological ea mehlala e fumanoeng ke endoscopic biopsy kapa laparotomy. Maemong a fetang 70%, ho kenella ke lymphocytic / plasmocytic, leha e ka ba eosinophilic ka karabelo e tlase kalafong. Li-infiltrate tse ling tse sa khonehang haholo ke neutrophilic (neutrophils) kapa granulomatous (macrophages).
Phekolo ea mafu a ho ruruha a mala ka likatse
Kalafo ea mafu a ho ruruha ha likatse likatseng e ipapisitse le motsoako oa phepo le li-immunomodulators mme, haeba e le teng, kalafo ea comorbidities.
kalafo ea lijo
Likatse tse ngata tse nang le IBD li fola ka matsatsi a 'maloa ka Lijo tsa hypoallergenic. Lebaka ke hore lijo li fokotsa substrate bakeng sa kholo ea baktheria, e eketsa ho monya mala le ho fokotsa bokhoni ba osmotic. Le ha ho fetola lijo tsena ho ka etsa hore limela tsa mala li be maemong a tloaelehileng, ho thata ho fokotsa mefuta ea likokoana-hloko e fetang bongata ba mala. Ho phaella moo, haeba ho e-na le ho pholletsa le mafu ka nako e le 'ngoe, lithibela-mafu li lokela ho fanoa ho thibela tšoaetso mokhoeng oa bile kapa mala ka lebaka la likarolo tsa katse (feline triad).
Haeba mala a maholo le ona a amehile, ts'ebeliso ea lijo tse phahameng tsa fiber e ka bonts'oa. Leha ho le joalo, e tla ba ngaka ea liphoofolo e tla bontša lijo tse ntlehali tsa likatse tse nang le IBD ho latela nyeoe ea hau.
Kalafo ea bongaka
Haeba u na le chelete e tlase ea b12 vithamine, katse e lokela ho tlatsetsoa ka lethal dose ea li-micrograms tse 250 ka mokhoa o le mong hang ka beke bakeng sa libeke tse 6. Kamora moo, libeke tse ling le tse ling tse 2 bakeng sa libeke tse ling tse 6 ebe khoeli le khoeli.
O metronidazole e sebetsa hantle hobane e loants'a likokoana-hloko le ho itšireletsa mafung, empa e tlameha ho sebelisoa ka nepo ho qoba litlamorao tse mpe liseleng tsa mala le neurotoxicity. Ka lehlakoreng le leng, ba sebelisa li-corticosteroids joalo ka prednisolone litekong tsa immunosuppressive. Kalafo ena e lokela ho etsoa, leha lijo li sa fetoloe ho lekola hypersensitivity ea lijo, likatseng tse bonts'ang tahlehelo ea boima ba 'mele le matšoao a silang lijo.
Kalafo e nang le prednisolone e ka qala ka 2 mg / kg / 24h ka molomo. Tekanyo, haeba ho na le ntlafatso, e bolokoa libeke tse ling tse 2 ho isa ho tse 4. Haeba matšoao a kliniki a fokotseha, lethal dose e fokotsoe ho 1 mg / kg / 24h. tekanyetso e tlameha ho fokotseha ho fihlela o fihlela lethal dose e tlase ka ho fetisisa e lumellang taolo ea matšoao.
Haeba li-corticosteroids li sa lekana, li lokela ho tsebisoa li-immunosuppressants tse ling, joalo ka:
- Chlorambucil ka tekanyo ea 2 mg / katse ka molomo lihora tse ling le tse ling tse 48 (bakeng sa likatse tse boima bo fetang 4 kg) kapa lihora tse ling le tse ling tse 72 (bakeng sa likatse tse boima bo ka tlase ho 4 kg). Palo e felletseng ea mali e lokela ho etsoa libeke tse ling le tse ling tse 2-4 haeba ho ka etsahala hore moko oa masapo o aplasia.
- Cyclosporine ka lethal dose ea 5 mg, / lik'hilograma / 24 lihora tse.
O kalafo ea mafu a bonolo a ho ruruha likatse li kenyelletsa:
- Lijo tsa Hypoallergenic matsatsi a 7 le tlhahlobo ea karabelo.
- Metronidazole matsatsi a 10 ka tekanyo ea 15mg / kg / 24 lihora tse ka molomo. Fokotsa lethal dose ka 25% libekeng tse ling le tse ling tse 2 ho fihlela o tsoa.
- Haeba ho se karabelo ka kalafo e boletsoeng ka holimo, prednisolone 2 mg / kg / 24h e lokela ho qalisoa e le mong kapa e kopane le metronidazole, e fokotsa lethal dose ka 25% libeke tse ling le tse ling tse 2 ho fihlela ha tekanyo e tlase e sebetsa.
Hona joale kaha u na le mefuta e fapaneng ea kalafo ea likatse tsa mafu a ho ruruha likatse, o kanna oa ba le tjantjello ea ho tseba mafu a atileng haholo likatseng. Se ke oa fetoa ke video e latelang:
Sengoloa sena se reretsoe ho fana ka tlhaiso-leseling feela, ho PeritoAnimal.com.br ha re khone ho fana ka kalafo ea bongaka ba liphoofolo kapa ho etsa mofuta ofe kapa ofe oa tlhahlobo. Re fana ka maikutlo a hore o ise phoofolo ea lapeng ho ngaka ea liphoofolo haeba e ka ba le boemo bofe kapa bofe bo sa thabiseng.
Haeba u batla ho bala lingoliloeng tse ling tse tšoanang le Lefu la ho ruruha ha Likokoana-hloko - Matšoao le Phekolo, Re khothaletsa hore o kenye karolo ea rona ea Mathata a mala.